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Publications by SCSB Faculty

Last Update: December, 2017

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  • 2012 Publications

    El Ayadi A, Stieren ES, Barral JM, Oberhauser AF, Boehning D. "Purification and aggregation of the amyloid precursor protein intracellular domain", J Vis Exp., 66:e4204 (2012).

    El Ayadi A, Stieren ES, Barral JM, Boehning D. "Ubiquilin-1 regulates amyloid precursor protein maturation and degradation by stimulating K63-linked polyubiquitination of lysine 688.", Proc Natl Acad Sci U S A. 109(33):13416-21 (2012).

    Spencer PS, Siller E, Anderson JF, Barral JM. "Silent substitutions predictably alter translation elongation rates and protein folding efficiencies.", J Mol Biol. 422(3):328-35 (2012).

    Navaratnarajah, C.K., Negi, S.S., Braun, W. and Cattaneo, R. "Membrane fusion triggering: three modules with different structure and function in the upper half of the measles virus attachment protein stalk.", J. Biol. Chem. 287(46):38543-38551 (2012).

    Apte-Sengupta, S., Negi, S.S., Leonard, V.H.J., Oezguen, N., Navaratnarajah, C.K., W. Braun, W. and Cattaneo, R. "Base of the measles virus fusion trimer head receives the signal that triggers membrane fusion.", J. Biol. Chem. 287(39):33026-33035 (2012).

    Oezguen, N., Power, T.D., Urvil, P., Feng, H., Pothoulakis, C., Stamler, J.S., Braun, W. and Savidge, T.C. "Clostridial toxins: Sensing a target in a hostile gut environment." Gut Microbes, 3(1):35-41 (2012).

    Lu, W., Negi, S.S., Oberhauser, A.F. and Braun, W. "Engineering proteins with enhanced mechanical stability by force-specific sequence motifs.", Proteins, 80(5):1308-1315 (2012).

    Tiwari, R., Negi, S.S., Braun, B., Braun, W., Pomes, A., Chapman, M.D., Goldblum, R.M. and Midoro-Horiuti, T. "Validation of a Phage Display and Computational Algorithm by Mapping a Conformational Epitope of Bla g 2.", Int. Arch. Allergy Immunol. 157(4):323-330 (2012).

    Bujalowski WM, Jezewska MJ. "Using structure-function constraints in FRET studies of large macromolecular complexes.", Methods Mol Biol. 875:135-64 (2012).

    Bujalowski WM, Jezewska MJ. "Fluorescence intensity, anisotropy, and transient dynamic quenching stopped-flow kinetics.", Methods Mol Biol. 875:105-33 (2012).

    Bussetta C, Choi KH. "Dengue virus nonstructural protein 5 adopts multiple conformations in solution.", Biochemistry 51(30):5921-31 (2012).

    Choi KH. "Viral polymerases." Adv Exp Med Biol. 726:267-304 (2012).

    Zandarashvili L, Vuzman D, Esadze A, Takayama Y, Sahu D, Levy Y, Iwahara J. "Asymmetrical roles of zinc fingers in dynamic DNA-scanning process by the inducible transcription factor Egr-1." Proc Natl Acad Sci U S A. 109(26):E1724-32 (2012).

    Yu S, Maillard RA, Gribenko AV, Lee JC. "The N-terminal capping propensities of the D-helix modulate the allosteric activation of the Escherichia coli cAMP receptor protein." J Biol Chem. 287(47):39402-11 (2012).

    Wicker JA, Whiteman MC, Beasley DW, Davis CT, McGee CE, Lee JC, Higgs S, Kinney RM, Huang CY, Barrett AD. "Mutational analysis of the West Nile virus NS4B protein." Virology. 426(1):22-33 (2012).

    Denner LA, Rodriguez-Rivera J, Haidacher SJ, Jahrling JB, Carmical JR, Hernandez CM, Zhao Y, Sadygov RG, Starkey JM, Spratt H, Luxon BA, Wood TG, Dineley KT. "Cognitive enhancement with rosiglitazone links the hippocampal PPARγ and ERK MAPK signaling pathways." J Neurosci. 32(47):16725-35a (2012).

    Gelman BB, Chen T, Lisinicchia JG, Soukup VM, Carmical JR, Starkey JM, Masliah E, Commins DL, Brandt D, Grant I, Singer EJ, Levine AJ, Miller J, Winkler JM, Fox HS, Luxon BA, Morgello S; "The National NeuroAIDS Tissue Consortium brain gene array: two types of HIV-associated neurocognitive impairment." PLoS One. 7(9):e46178 (2012).

    Finnerty CC, Ju H, Spratt H, Victor S, Jeschke MG, Hegde S, Bhavnani SK, Luxon BA, Brasier AR, Herndon DN. "Proteomics improves the prediction of burns mortality: results from regression spline modeling." Clin Transl Sci. 5(3):243-9 (2012).

    Morais MC. "The dsDNA packaging motor in bacteriophage ø29." Adv Exp Med Biol. 726:511-47 (2012).

    Saha M, Morais MC. "FOLD-EM: automated fold recognition in medium- and low-resolution (4-15 Å) electron density maps." Bioinformatics. 28(24):3265-73 (2012).

    Zhao W, Saha M, Ke A, Morais MC, Jardine PJ, Grimes S. "A three-helix junction is the interface between two functional domains of prohead RNA in ø29 DNA packaging." J Virol. 86(21):11625-32 (2012).

    Harjes E, Kitamura A, Zhao W, Morais MC, Jardine PJ, Grimes S, Matsuo H. "Structure of the RNA claw of the DNA packaging motor of bacteriophage Φ29." Nucleic Acids Res. 40(19):9953-63 (2012).

    Kaiser CM, Bujalowski PJ, Ma L, Anderson J, Epstein HF, Oberhauser AF. "Tracking UNC-45 chaperone-myosin interaction with a titin mechanical reporter." Biophys J. 102(9):2212-9 (2012).

    Ma L, Xu M, Oberhauser AF. "Single-molecule force spectroscopy of polycystic kidney disease proteins." Methods Mol Biol. 875:297-310 (2012).

    Shavkunov A., Panova N., Prasai A.,Veselenak R., Bourne N., Stoilova-McPhie S., Laezza F. "Bioluminescence methodology for the detection of protein:protein interactions within the voltage-gated sodium channel macromolecular complex." Assay Drug Dev Technol 10(2):148-60 (2012).

    Rusu M, Bonneau R, Holbrook MR, Watowich SJ, Birmanns S, Wriggers W, Freiberg AN. "An assembly model of rift valley Fever virus." Front Microbiol. 3:254 (2012).

    Tomlinson SM, Watowich SJ. "Use of parallel validation high-throughput screens to reduce false positives and identify novel dengue NS2B-NS3 protease inhibitors." Antiviral Res. 93(2):245-52 (2012).

    Weaver SC, Osorio JE, Livengood JA, Chen R, Stinchcomb DT. "Chikungunya virus and prospects for a vaccine." Expert Rev Vaccines. 11(9):1087-101 (2012).

    Adams AP, Navarro-Lopez R, Ramirez-Aguilar FJ, Lopez-Gonzalez I, Leal G, Flores-Mayorga JM, Travassos da Rosa AP, Saxton-Shaw KD, Singh AJ, Borland EM, Powers AM, Tesh RB, Weaver SC, Estrada-Franco JG. "Venezuelan equine encephalitis virus activity in the Gulf Coast region of Mexico, 2003-2010." PLoS Negl Trop Dis. 6(11):e1875 (2012).

    Forrester NL, Guerbois M, Seymour RL, Spratt H, Weaver SC. "Vector-borne transmission imposes a severe bottleneck on an RNA virus population." PLoS Pathog. 8(9):e1002897 (2012).

    Nasar F, Palacios G, Gorchakov RV, Guzman H, Da Rosa AP, Savji N, Popov VL, Sherman MB, Lipkin WI, Tesh RB, Weaver SC. "Eilat virus, a unique alphavirus with host range restricted to insects by RNA replication." Proc Natl Acad Sci USA 109(36):14622-7 (2012).

    Weaver SC, Winegar R, Manger ID, Forrester NL. "Alphaviruses: population genetics and determinants of emergence." Antiviral Res. 94(3):242-57 (2012).

    Kenney JL, Adams AP, Gorchakov R, Leal G, Weaver SC. "Genetic and anatomic determinants of enzootic Venezuelan equine encephalitis virus infection of Culex (Melanoconion) taeniopus." PLoS Negl Trop Dis. 6(4):e1606 (2012).

    Gorchakov R, Wang E, Leal G, Forrester NL, Plante K, Rossi SL, Partidos CD, Adams AP, Seymour RL, Weger J, Borland EM, Sherman MB, Powers AM, Osorio JE, Weaver SC. "Attenuation of Chikungunya virus vaccine strain 181/clone 25 is determined by two amino acid substitutions in the E2 envelope glycoprotein." J Virol. 86(11):6084-96 (2012).

    Haddow AD, Schuh AJ, Yasuda CY, Kasper MR, Heang V, Huy R, Guzman H, Tesh RB, Weaver SC. "Genetic characterization of Zika virus strains: geographic expansion of the Asian lineage." PLoS Negl Trop Dis. 6(2):e1477 (2012).

    Chen H, Tsalkova T, Mei FC, Hu Y, Cheng X, Zhou J. "5-Cyano-6-oxo-1,6-dihydro-pyrimidines as potent antagonists targeting exchange proteins directly activated by cAMP." Bioorg Med Chem Lett. 22(12):4038-43 (2012).

    Tsalkova T, Mei FC, Cheng X. "A fluorescence-based high-throughput assay for the discovery of exchange protein directly activated by cyclic AMP (EPAC) antagonists." PLoS One. 7(1):e30441 (2012).

    White MA, Li S, Tsalkova T, Mei FC, Liu T, Woods VL Jr, Cheng X. "Structural analyses of a constitutively active mutant of exchange protein directly activated by cAMP." PLoS One. 7(11):e49932 (2012).

    Tsalkova T, Mei FC, Li S, Chepurny OG, Leech CA, Liu T, Holz GG, Woods VL Jr, Cheng X. "Isoform-specific antagonists of exchange proteins directly activated by cAMP." Proc Natl Acad Sci USA. 109(45):18613-8 (2012).