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SCSB_Logo-Sealy Center for Structural Biology and Molecular Biophysics















Our mission is to unlock the basic relationships between macromolecular sequence, structure and function, and to understand and treat disease. This mission is pursued through a three-fold strategy that involves:

  • conduct basic research in the fields of structural, physical, and quantitative biology;
  • train investigators in molecular biophysics, and structural and computational biology;
  • and partner with complementary research efforts on campus to foster mutual scientific goals and to build translational research programs.



Registration NOW OPEN for the 27th SCSB Annual Symposium to be held on April 29, 2023, Health Education Center (HEC) Room 1.200, UTMB Galveston.
Dr. Gabrielle Rudenko has been featured on SBGrid Member Tales.

Employment Opportunities

Employment Opportunities

The Center currently has no open faculty positions.

Postdoc position openings in these research groups:

  • Prof. K. H. Choi
  • Postdoctoral positions in structural biology are available in Dr. Kay Choi's laboratory at the University of Texas Medical Branch to participate in NIH-funded projects. We use a combination of X-ray crystallography, cryo-electron microscopy, and biochemistry to investigate the structure and mechanism of viral macromolecular complexes. Experience in either X-ray crystallography or cryo-electron microscopy is required.

    The X-ray crystallography resources include two X-ray area detector systems, a Phoenix crystallization robot, a Minstrel crystal imaging robot, and an Alchemist liquid handling robot. The cryo-EM facility includes two JOEL 200 keV cryo-EM microscopes for high-resolution imaging work, an FEI vitrobot, and a BSL-3 room for viral and pathogen work.

    Interested parties should send a CV, a brief statement of research interests, and a list of 2-3 references to Dr. Kay Choi via e-mail at

  • Prof. Gabrielle Rudenko
  • An NIH-funded Post-doctoral fellowship position is available at the University of Texas (UTMB) located in the greater Houston area in the research team of Dr. Gabrielle Rudenko. We study the protein interaction network at synapses (the contact and communication point between neurons in neural circuits), and processes that control synapse development. Many of our proteins of interest serve as potential novel therapeutic targets for neurological disorders. The ideal candidate will be an enthusiastic and dynamic structural biologist with experience in biochemistry, crystallography and/or cryoEM who is interested in combining the fields of structural biology and neuroscience.

    Qualifications: Experience in protein crystallography, molecular biology, bacterial/insect cell culture, protein purification, crystallization and biophysical techniques. Good written and oral communication skills in English. Ability and desire to work as part of a highly motivated and collaborative team.

    To apply, please e-mail the following to CV, contact information for three references (address, phone and e-mail), a list of your experimental expertise and skills relevant to this position. Visa sponsorship is available for non-US nationals. You must have received you PhD degree to be eligible. For more information please visit Dr. Gabrielle Rudenko's website.

  • Prof. Guy Nir
  • For more information please visit Dr. Guy Nir's website.