Lawrence C. Sowers, PhD

Professor and Chair
Department of Pharmacology & Toxicology

Research

His work has involved the chemistry and biology of DNA damage resulting from both carcinogens and cancer chemotherapy agents. More recently, he has focused upon damage to DNA resulting from reactive molecules generated by activated inflammatory cells including eosinophils and neutrophils. He has recently demonstrated how certain inflammation-mediated DNA damage products could mimic epigenetic signals, perhaps explaining how inflammation could result in heritable changes in genes expression important for the silencing of tumor suppressor genes in the development of cancer, and how early exposure to agents that trigger inflammation could influence disease susceptibility later in life. His laboratory has trained numerous Ph.D., M.D. and M.D./Ph.D. students over the years and he looks forward to training further students within the context of this translational and interdisciplinary program in Galveston.

Publications

 

Lawrence C. Sowers, PhD

Tel: (409) 772-9678
Fax: (409) 772-9648
E-mail: lasowers@utmb.edu
Campus Location:3.336 Basic Science Bldg
Mail Route: 0617